The Murray Lab is located on the University of Iowa campus in the Medical Laboratories building of the Carver College of Medicine.
Campus Address
2182 MLPostal Address
Department of Pediatrics University of Iowa 500 Newton Road 2182 ML Iowa City, IA 52242Main Office 319-384-4464
Dr. Murray 319-335-6897
Fax Number 319-335-6970
Our lab applies tools from a variety of disciplines, particularly those of genetics, molecular biology, embryology and epidemiology to study birth defects and prematurity and its complications.
Current projects include strategies to identify and characterize genes involved in several inherited human disorders.
In one example, the Van der Woude syndrome, we have identified the gene (IRF6) in collaboration with Brian Schutte and are now applying this finding to study its role in facial development. Other genes under study in the lab include those involved in language development and the causes of myopia.
We have recently begun a large project to look at the gene and environmental causes of prematurity and its complications which currently affects 500,000 children a year in the US. We are using genome-wide strategies, including family linkage and association.
Many of our studies are carried out using large population and epidemiologic studies of children with craniofacial anomalies or preterm birth, particularly from the Philippines, Denmark, Argentina and Brazil, and we work in close collaboration with investigators in these countries. We are also involved in studies of the prevention and better treatment of children with birth defects. Graduate students and postdoctoral fellows in the lab serve in leadership roles for these projects and have primary responsibility for project design and implementation. We are strongly committed to providing opportunities for students in the classroom, the laboratory and in fieldwork to develop their interests and expertise in the application of genetic tools to an understanding of human disease.
The old content site had a really quick and dirty method of pulling our published paper PDFs from a local file system using PHP. Essentially it would blindly take the filename from the URL and send it to the browser, which is a horribly insecure way of doing such a thing but I needed to get things done quickly, and I shudder to think of what would have happened if someone discovered a way to mess with it.
In my presentation in September, I made a number of clams that could seem outrageous when taken just by themselves. One underlying concept that I didn’t directly express, but there was a subtle under-text, was the current process of modern scientific research (idea, grant, investigate, test, publish) is now on a limited lifespan.
If you’re working on the cleft side of the lab, you’ve probably heard of the FaceBase project, but if you haven’t read more about it!
This error message has been seen in the web after trying to update a barcode using that action. This has been forwarded on to Progeny. They are looking into it, but said that you should be able to log back in after a few minutes and the lock will be released.
If you get an error message like the one below in Progeny web when you edit information in a sample data sheet, try clicking on the datasheet outside of the field you are editing before closing out and that should take care of it. Read More…
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